Treatment
Sep 07, 2010
 Pediatric Weight Management In Canada
How does the landscape for pediatric weight management in Canada look today? This question was addressed by Geoff Ball (University of Alberta) and colleagues in a paper just published in the International Journal of Pediatric Obesity. |
Aug 06, 2010
Time Course of Incretin Responsiveness to Bariatric Surgery
A paper by Bose and colleagues from Columbia University, published in the Journal of Diabetes suggests that both mechanisms follow different timelines and may therefore independently contribute to improvements in glucose control after gastric bypass surgery. |
Jul 12, 2010
FDA to review first of 3 new weight loss drugs
WASHINGTON — Dieters, doctors and investors get their first extensive look at the first of a trio of new weight loss drugs this week. The hope is that the new drugs can succeed where many others have failed: delivering significant weight loss without risky side effects. |
Jun 02, 2010
FDA accepted the New Drug Application for its candidate Contrave
Recently Orexigen Therapeutics, Inc. (OREX - Snapshot Report) received a boost when the US Food and Drug Administration (FDA) accepted the New Drug Application for its candidate Contrave (naltrexone SR/bupropion SR). The candidate, a combination therapy, aims to address physiological and behavioral causes of obesity.
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May 19, 2010
Fighting cancer: Diet, scant exercise problems
(Reuters) - The United States does not produce or import anywhere near enough fruits and vegetables to provide Americans the right kind of diet to prevent cancer, government researchers said on Wednesday. |
Apr 19, 2010
Anti-Obesity Drug Slated for FDA Review
Anti-obesity drug, Qnexa, is set to go in front of an FDA advisory panel in July. Makers of Qnexa hope it will be available by the end of the year. |
Mar 24, 2010
Obesity, a disease recorded by physician in their patient’s notes ?
Yesterday, I chaired a round table organised by the Canadian Obesity Network on behalf of the Public Health Agency of Canada on the development of tools and aids that would help Canadian primary care physicians and other health professionals improve their ability to prevent and treat obesity. |
Feb 01, 2010
Primary Care Needs to Restructure Its Approach to Obesity
As report after report expresses concern about the rising prevalence and health impacts of obesity, it is becoming increasingly clear that business as usual is not going to work in addressing this epidemic. |
Feb 01, 2010
Weight Loss Amplifies DASH Diet Effects on Blood Pressure
While excess weight is probably one of the most important risk factors for high blood pressure, weight loss is certainly one of the most effective treatments. |
Jan 28, 2010
Top obesity drug sibutramine being suspended in Europe
A leading obesity drug is being suspended from use in the UK amid fears it increases the risk of heart attacks and strokes. |
Jan 28, 2010
New campaign to screen young children for obesity
Should children be screened for obesity so they can be treated? |
Nov 30, 2009
Doctors embrace bariatric surgery as effective treatment for diabetes
Fifty international scientific and medical experts have issued a "consensus statement" declaring that bariatric surgery should be considered a treatment option for patients with Type 2 diabetes, even if they are not extremely obese. |
Nov 30, 2009
Psychological Assessment and Management of Bariatric Surgical Patients: What and Why?
All current guidelines highlight the need for mental health assessments in individuals considering bariatric surgery.
But what exactly should be assessed, how important is mental health as a predictor of outcomes and what is the risk for exacerbation of mental health problems after surgery (remember: bariatric surgery has been reported to substantially increase the risk of suicides and accidental deaths). |
Nov 23, 2009
Buddy system helps boost weight loss
Dieters can boost their weight loss if they clean up their act at home and get a partner to lose weight with them, a new study shows. |
Nov 17, 2009
Buddy system helps boost weight loss
Dieters can boost their weight loss if they clean up their act at home and get a partner to lose weight with them, a new study shows. |
Oct 29, 2009
Good Tidings for Obesity Treatment?
Liraglutide is a glucagon-like peptide-1 (GLP-1) analogue with a 97% structural homology to human GLP-1, a gut hormone that plays a key role in the regulation of glucose homeostasis, gut motility and possibly hunger and appetite. |
Oct 25, 2009
Super-Obesity Ups Risk of Bariatric Surgery Death
(Ivanhoe Newswire) -- Veterans classified as super-obese and those with a higher chronic disease burden appeared more likely to die within a year of having bariatric surgery, according to a new study. |
Oct 25, 2009
3 new prescription diet drugs may soon help obese
At least three new prescription diet drugs are in the final stages of development as pharmaceutical companies race to see which one will have the next big diet medication to hit the market. |
Oct 18, 2009
Weight Loss Reduces Liver Fat
Despite the small size of this study, the results are undisputable: weight reduction achieved through lifestyle intervention leads to improvements in liver histology in NASH. |
Sep 29, 2009
Overweight Teens Turn to Surgery
About 70 percent of obese adolescents grow up to become obese adults. It's a dangerous cycle of overeating that's hard to break. But is surgery safe for someone so young? Some teenagers say going under the knife is their only option. |
Sep 05, 2009
New Molecule Combats Diabetes and Obesity
The rise in obesity and the onset of type 2 diabetes is increasing at epidemic rates, affecting more than 180 million people worldwide. A group from the Ecole Polytechnique Fédérale de Lausanne (EPFL) may have found a new weapon in the fight against these disorders. |
Aug 28, 2009
New Drug Fights Fat, Lowers Cholesterol and Reverses Diabetes
Researchers searching for a cure for obesity said on Thursday they have developed a drug that not only makes mice lose weight, but reverses diabetes and lowers their cholesterol, too. |
Aug 25, 2009
Obesity drug fears investigated
US authorities are investigating concerns an anti-obesity drug widely available over the counter at chemists may cause liver damage. |
Mar 17, 2008
TREATMENT: Anti-obesity pill 'may be ready in 10 years'
A pill to treat obesity could be available in a decade after a breakthrough in the understanding of how genetic factors make some people much more likely to put on weight. |
Jul 21, 2009
Yale Discovery May Open Door To Drug That Cuts Appetite And Boosts Energy
Reductions in the levels of the enzyme prolylcarboxypeptidase (PRCP) led to weight loss and a decreased risk of type 2 diabetes in mice. |
Jul 21, 2009
Orexigen's Obesity Drug Contrave Meets FDA Benchmark
Orexigen Therapeutics, yesterday anounced that all three remaining trials in their Contrave Obesity Research Phase 3 Program succesfully meet critical FDA benchmarks and that it hopes to file a New Drug Application (NDA) with the US Food and Drug Administration (FDA) in the first half of 2010. |
May 14, 2009
From Outrage to Engage
As Scientific Director of the Canadian Obesity Network, I have long maintained that the solutions to obesity are everyone’s responsibility and we therefore need to involve all relevant stakeholders in trying to find solutions. |
May 13, 2009
Gastric Bypass Surgery Cuts Cancer Mortality in Half
For anyone still skeptical about the tremendous benefit of bariatric surgery for severe obesity in reducing cancer mortality, here is a new study by Ted Adams and colleagues from the University of Utah, published in the latest issue of OBESITY. |
Jan 14, 2009
Surgical vs. Non-Surgical Weight-Loss Maintenance
Summary: some people can indeed lose significant amounts of weight and keep it off, but they need to exercise more, avoid fast food, display high dietary restraint and better not be depressed or stressed out (even then, there is some weight regain). For others, surgery may very well be a more realistic option. |
Jan 09, 2009
Contrave Weighs in Lighter Than Expected
Orexigen Therapeutics Inc on Thursday reported the results of their first 56-week phase III study on contrave, a combination of the antidepressant bupropion and the opioid-antagonist naltrexone (both drugs have been on the market for other indications for over 20 years). |
Dec 16, 2008
Oprah's 200 pounds – so what?
By making her weight topic No. 1, she invites us to judge her by it. It's time she gives herself – and us – a break |
Nov 11, 2008
Pfizer ends development of obesity drug
New York - Pfizer Inc on Wednesday became the latest drugmaker to abandon an obesity treatment that works by blocking the receptors in the brain that makes people hungry after smoking marijuana. |
Nov 09, 2008
Work on Antiobesity Drugs Is Halted
French drug maker Sanofi-Aventis SA said it is discontinuing clinical trials of antiobesity drug Acomplia. |
Nov 01, 2008
New drug target in obesity: Fat cells make lots of melanin
New article in the FASEB Journal shows for the first time that fat cells hold the secret to good health |
Oct 31, 2008
Effect of tesofensine on bodyweight
Weight-loss drugs produce an additional mean weight loss of only 3—5 kg above that of diet and placebo over 6 months, and more effective pharmacotherapy of obesity is needed. We assessed the efficacy and safety of tesofensine—an inhibitor of the pres |
Oct 27, 2008
Rimonabant Suspended in Europe
The big obesity news yesterday was the recommendation of the European Medicines Agency (EMEA) to suspend the marketing authorisation of the CB-1 antagonist Acomplia® (rimonabant) across the European Union (EU). |
Oct 04, 2008
UPDATE 2-Merck ends development of obesity drug taranabant
NEW YORK, Oct 2 (Reuters) - Merck & Co (MRK.N: Quote, Profile, Research, Stock Buzz) has stopped development of its experimental obesity drug taranabant after data in a late-stage clinical study found more side effects at higher doses, the drug maker |
Oct 01, 2008
Public Bariatric Speciality Clinic in Ontario
Yesterday, the Globe and Mail wrote an extensive article on Dr. Sean Wharton, an internist, who runs a clinic that delivers a full range of bariatric medical care within the Ontario public health care system. |
Aug 02, 2008
AMPK and PPARd AgonistsAre Exercise Mimetics
The benefits of endurance exercise on general health make it desirable to identify orally active agents that would mimic or potentiate the effects of exercise to treat metabolic diseases. |
Jun 29, 2008
Sanofi obesity drug gets final okay from UK's NICE
LONDON, June 25 (Reuters) - Sanofi-Aventis won a final green light for its obesity drug Acomplia from Britain's cost-effectiveness watchdog NICE on Wednesday, clearing the way for doctors to prescribe it on the state health service. |
Jun 06, 2008
Sanofi-Aventis anti-obesity drug cited by UK regulator in 5 deaths
Sanofi-Aventis anti-obesity drug Acomplia has been cited in relation to five deaths and 720 adverse drug reactions in the UK, according to figures published on Tuesday by the Medicines and Healthcare products Regulatory Agency (MHRA). |
May 13, 2008
The Science of Obesity: When Willpower Isn't Enough
BOSTON, Mass. (Ivanhoe Newswire) – From low carbs to high protein. One day soon, weight loss will go beyond these diets and even bariatric surgery. |
Mar 02, 2008
CBC TV’s “The National” aired a report on the state of obesity surgery in Canada.
The story is about how, despite its proven safety and benefits, obesity surgery in Canada is hard to come by.
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Jan 17, 2008
Endobarrier for Weight Loss
Imagine reaping the benefits of gastric bypass without the risks of surgery. Early results from the study of a new device are finding just that potential.
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Nov 25, 2007
No magic pills: Anti-obesity drugs provide only modest weight loss, study shows
Most severely overweight patients taking anti-obesity drugs will realize only modest weight loss: researchers. |
Nov 13, 2007
Stopping That Rebound In Weight
Ask U.S. adults if they're trying to lose weight, and three out of four say "yes," polls show. |
Oct 19, 2007
Kids Have Trouble Keeping Weight Off
Heavy children who lost weight kept the pounds off better through weight maintenance follow-up, but even that wasn't terribly successful over two years, researchers reported. |
Oct 19, 2007
The gastric bypass diet outlines what you can eat and how much after gastric bypass surgery. Find out ways to establish new eating habits for successful weight loss
The gastric bypass diet outlines what you can eat and how much after gastric bypass surgery. Find out ways to establish new eating habits for successful weight loss. From the Mayo Clinic. |
Oct 19, 2007
Weight-loss outcomes: a systematic review and meta-analysis of weight-loss clinical trials with a minimum 1-year follow-up |
Sep 11, 2007
Arena Pharmaceuticals Continues Phase 3 BLOOM Obesity Trial Following Independent Echocardiogaphic Data Safety Monitoring Board Review
...an independent Echocardiographic Data Safety Monitoring Board (the Board or EDSMB) found no reason to stop the ongoing pivotal Phase 3 trial, BLOOM (Behavioral modification and Lorcaserin for Overweight and Obesity Management). The BLOOM trial is |